[Solved] How does the affinity of M6P receptor proteins for the mannose 6-phosphate marker (on proteins ultimately bound for the lysosome)

How does the affinity of M6P receptor proteins for the mannose 6-phosphate marker (on proteins ultimately bound for the lysosome) change between the trans-Golgi and endosome? Which coat protein is mainly responsible for their transport from the TGN to the endosome?

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